Beta: Bioprinting engineering technology for academia

Higher STEM education is a field of growing potential, but too many middle school and high school students are not testing proficiently in STEM subjects. The BETA team worked to improve biology classroom engagement through the development of technologies for high school biology experiments. The BETA project team expanded functionality of an existing product line to allow for better student and teacher user experience and the execution of more interesting experiments. The BETA project’s first goal was to create a modular incubating Box for the high school classroom. This Box, called the BETA Box was designed with a variety of sensors to allow for custom temperature and lighting environments for each experiment. It was completed with a clear interface to control the settings and an automatic image capture system. The team also conducted a feasibility study on auto calibration and dual-extrusion for SE3D’s existing 3D bioprinter. The findings of this study led to the incorporation of a force sensor for auto calibration and the evidence to support the feasibility of dual extrusion, although further work is needed. These additions to the current SE3D educational product line will increase effectiveness in the classroom and allow the target audience, high school students, to better engage in STEM education activities

Information Systems and Health Care XI: Public Health Knowledge Management Architecture Design: A Case Study

This paper presents the results of a case study based on the creation of a knowledge management program architecture in the public health domain. Data were gathered in the study using the program logic model as a framework for conducting a series of six focus groups. Results illustrate major elements and branches of the final design with commentary on the knowledge management implications of outcomes of this design effort. The methodology used provides an artifact in the form of an information requirement process that may be suited to other contexts. Discussion of findings focuses on six themes regarding knowledge management systems, particularly in the public health context and during the design process

Information Systems and Healthcare XXXV: Health Informatics Forums for Health Information Systems Scholars

The use of technology in health care settings is an area of increasing interest to information systems researchers. An awareness of journals and conferences that focus on this innately interdisciplinary field is necessary if researchers in related domains, such as information systems, intend to connect methodologies, insights, and perspectives to advance health IT knowledge. This study fills a void in the literature by providing an initial peer ranking of dedicated health informatics journals and related conferences as guidance for those interested in learning more about and/or publishing in this field. Results indicate that there are at least forty-five journals that researchers may want to consider in conducting health informatics work

Champion Networks in Federated Interorganizational Systems: Case Studies in Telemedicine

Champions are critical to the success of an information system implementation. Research shows that success in implementing a large information system may hinge on there being more than one type of champion. This study investigates the types of champions used in federated inter-organizational systems (FIOS) in a state telemedicine context. Case studies were conducted in Georgia, Pennsylvania, Ohio, and Wisconsin to identify the network of champions in state telemedicine systems. We found that FIOS that relied on a network of champions, including a sponsorship champion at the state level, as well as a technical champion and user champion at site locations, were more successful than those that lacked such a network. We suggest that our model of champions in FIOS applies not only to state telemedicine, but also to any large-scale system implementation spanning a federation of loosely coupled organizations

Comparison of Methods to Determine Maritime Safety Zones for LNG Terminals

PresentationA Maritime Safety Zone is defined by the U.S. Coast Guard as a water area, shore area, or water and shore area combined to which, for safety or environmental purposes, access is limited to authorized persons, vehicles, or vessels. A Maritime Safety Zone is established to prevent interference with safe navigation and tug maneuvers, to exclude third party access in order to reduce ignition probability, to aid in emergency preparation, and to protect the public from being exposed to potential harm. USCG also defines a Maritime Security Zone for protection against intentional threats, and this is usually larger than the Safety Zone. The USCG requires that a Maritime Safety Zone be defined before a Letter of Recommendation is given. While the Canada Marine Act only suggests that a port authority may establish Traffic Control Zones, the USCG suggests using the Sandia study as guidance for determining Maritime Safety and Security Zones. Though there are guidance documents, no standard method is currently available for determining site specific Maritime Safety Zones applicable to accidental spills that could occur at the waterfront configuration of the terminal. A common methodology would enable Safety Zones to be more properly defined and create safer waterways. Two types of approaches have been proposed by DNV GL in this paper to determine the Safety Zones surrounding LNG terminals from accidental spills. A deterministic approach is based on a single maximum credible event among a set of representative scenarios that have been modeled. This approach may conservatively produce a very large hazard distance depending on the consequence of the maximum credible scenario. A probabilistic approach is a risk based approach which associates the consequence (the thermal radiation intensities and the flammable vapor dispersion distances) with the likelihood of having such a consequence. A probabilistic approach provides a more realistic basis for making informed decisions

Position as a behavioral property of subjects : the case of old Irish

A subject analysis of oblique subject-like arguments remains controversial even across the modern languages where the available data are not finite: while such arguments are considered syntactic subjects in Icelandic, they have more often been analyzed as objects in Lithuanian, for example. This issue has been left relatively unattended for the ancient Indo-European languages outside of Sanskrit (Hock 1990), Gothic (Barðdal & Eythórsson 2012) and Ancient Greek (Danesi 2015). In this article, we address the status of oblique subject-like arguments in Old Irish, whose strict word order enables us to compare the position (relative to the verb and other arguments) of nominative subject arguments of the canonical type to oblique subject-like arguments. We first establish a baseline for neutral word order of nominative subjects and accusative objects and then compare their distribution to that of oblique subject-like arguments under two conditions: i) on a subject analysis and ii) on an object analysis. The word order distribution differs significantly across the two contexts when the oblique arguments are analyzed as syntactic objects, but not when they are analyzed as syntactic subjects. These findings add to the growing evidence that oblique subject-like arguments should be analyzed as syntactic subjects, although their coding properties are non-canonical

Argument structure, conceptual metaphor and semantic change : how to succeed in Indo-European without really trying

In contrast to grammaticalization studies of lexical verbs changing into auxiliaries, the realm of semantic changes associated with lexical verbs is an understudied area of historical semantics. We concentrate on the emergence of verbs of success from more semantically concrete verbs, uncovering six conceptual metaphors which all co-occur with non-canonical encoding of subjects in Indo-European. Careful scrutiny of the relevant data reveals a semantic development most certainly inherited from Indo-European; hence, we reconstruct a DAT-‘succeeds’ construction at different levels of schematicity for Proto-Indo-European, including a novel reconstruction of a conceptual metaphor, success is motion forward, and the mapping between this metaphor and the verb-class-specific argument structure construction. Hence, this article offers a systematic analysis of regularity in semantic change, highlighting the importance of predicate and argument structure for lexical semantic developments

Weight Loss and Illness Severity in Adolescents With Atypical Anorexia Nervosa.

BACKGROUND:Lower weight has historically been equated with more severe illness in anorexia nervosa (AN). Reliance on admission weight to guide clinical concern is challenged by the rise in patients with atypical anorexia nervosa (AAN) requiring hospitalization at normal weight. METHODS:We examined weight history and illness severity in 12- to 24-year-olds with AN (n = 66) and AAN (n = 50) in a randomized clinical trial, the Study of Refeeding to Optimize Inpatient Gains (www.clinicaltrials.gov; NCT02488109). Amount of weight loss was the difference between the highest historical percentage median BMI and admission; rate was the amount divided by duration (months). Unpaired t tests compared AAN and AN; multiple variable regressions examined associations between weight history variables and markers of illness severity at admission. Stepwise regression examined the explanatory value of weight and menstrual history on selected markers. RESULTS:Participants were 16.5 ± 2.6 years old, and 91% were of female sex. Groups did not differ by weight history or admission heart rate (HR). Eating Disorder Examination Questionnaire global scores were higher in AAN (mean 3.80 [SD 1.66] vs mean 3.00 [SD 1.66]; P = .02). Independent of admission weight, lower HR (β = -0.492 [confidence interval (CI) -0.883 to -0.100]; P = .01) was associated with faster loss; lower serum phosphorus was associated with a greater amount (β = -0.005 [CI -0.010 to 0.000]; P = .04) and longer duration (β = -0.011 [CI -0.017 to 0.005]; P = .001). Weight and menstrual history explained 28% of the variance in HR and 36% of the variance in serum phosphorus. CONCLUSIONS:Weight history was independently associated with markers of malnutrition in inpatients with restrictive eating disorders across a range of body weights and should be considered when assessing illness severity on hospital admission

Draft Genome Sequences of Four Aeromonas salmonicida subsp. achromogenes Strains, 23051, 23053, 23055, and 23056, Isolated from Senegalese Sole ( Solea senegalensis )

International audienceThe bacterial species Aeromonas salmonicida officially has five subspecies. A large majority of the currently available sequences come from Aeromonas salmonicida subsp. salmonicida, which causes furunculosis in salmonids. We present the genomic sequences of four Aeromonas salmonicida subsp. achromogenes strains. This will help increase the robustness of genomic analyses for this subspecies